The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
Oct. 29, 2018
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Gregory C. Ippolito, Austin, TX (US);
Jonathan R. Mcdaniel, Austin, TX (US);
William N. Voss, Austin, TX (US);
George Georgiou, Austin, TX (US);
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); C07K 16/30 (2006.01); C12Q 1/6881 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C07K 16/3069 (2013.01); C12Q 1/6881 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01);
Abstract
Methods are provided for identifying tumor-specific antibodies and/or T-cell receptors by paired mRNA sequencing from individual immune cells in sentinel lymph nodes and comparison of these sequences with corresponding mass spectroscopy data from a subject having a cancer. Novel tumor-specific antibodies (e.g., NY-ESO-1-binding antibodies) are also provided.