The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
May. 25, 2018
Applicants:
Universite DE Rennes 1, Rennes, FR;
Centre National DE LA Recherche Scientifique—cnrs—, Paris, FR;
Inventors:
Reynald Gillet, Le Verger, FR;
Charlotte Guyomar, Porspoder, FR;
Assignees:
UNIVERSITE DE RENNES 1, Rennes, FR;
CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE—CNRS, Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/70 (2006.01); G01N 33/58 (2006.01); C12N 15/74 (2006.01); C12N 15/78 (2006.01); C12Q 1/02 (2006.01); C12Q 1/18 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C12N 15/70 (2013.01); C12N 15/74 (2013.01); C12N 15/746 (2013.01); C12N 15/78 (2013.01); C12Q 1/025 (2013.01); C12Q 1/18 (2013.01); G01N 21/6486 (2013.01);
Abstract
The present invention relates to a reporter system for trans-translation based on the reassembly of GFP and on the capacity of tmRNA to add a peptide tag to a protein blocked on a ribosome. The invention also relates to the in vivo or in vitro use of this reporter system for studying trans-translational activity and for identifying compounds capable of inhibiting trans-translation and therefore capable of being of interest as antibiotics.