The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2024

Filed:

Jul. 27, 2020
Applicant:

University of South Carolina, Columbia, SC (US);

Inventors:

Ehsan Jabbarzadeh, Columbia, SC (US);

Christopher Wu, Matthews, NC (US);

Assignee:

UNIVERSITY OF SOUTH CAROLINA, Columbia, SC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/34 (2006.01); C12M 1/12 (2006.01); C12M 1/42 (2006.01); C12M 1/00 (2006.01); C12M 1/32 (2006.01); C08L 33/26 (2006.01); C08L 33/10 (2006.01);
U.S. Cl.
CPC ...
C12M 41/12 (2013.01); C12M 23/20 (2013.01); C12M 25/14 (2013.01); C12M 35/02 (2013.01); C12M 35/04 (2013.01); C08L 33/10 (2013.01); C08L 33/26 (2013.01); C12M 23/12 (2013.01);
Abstract

Biocompatible, mechanically-dynamic thermoresponsive devices, methods for forming the devices, and exemplary applications for the devices are described. The devices include a series of wells therein and provide for temperature-controlled mechanostimulation of single cells or groups of cells that can be retained in the wells of a device. Mechanostimulation can be single instance of any duration, continuous, or regular or irregular cyclic mechanostimulation of single cells, cell clusters, cell spheroids, or organoids and may be utilized in any of a variety of biomedical applications including, without limitation, cellular engineering, cellular phenotyping, and drug discovery/screening.


Find Patent Forward Citations

Loading…