The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
May. 08, 2017
Applicant:
Crescendo Biologics Limited, Cambridge, GB;
Inventors:
Brian McGuinness, Cambridge, GB;
Colette Johnston, Cambridge, GB;
Assignee:
CRESCENDO BIOLOGICS LIMITED, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); C12N 5/0783 (2010.01); A61K 35/17 (2015.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01); C07K 16/30 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/3069 (2013.01); A61K 35/17 (2013.01); A61K 39/0011 (2013.01); A61P 35/00 (2018.01); C07K 16/00 (2013.01); C12N 5/0646 (2013.01); A61K 2039/5158 (2013.01); C07K 2317/569 (2013.01); C07K 2319/03 (2013.01);
Abstract
The invention relates to chimeric antigen receptors (CAR) that comprise one or more single human variable domain antibody and cells that express such CAR. In particular, the invention relates to CARs that include multiple single human variable domain antibodies. In a particular embodiment, the one or more single human variable domain antibody binds to prostate membrane antigen.