The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2024

Filed:

May. 30, 2019
Applicants:

Kanoncure, Inc., Yonago, JP;

National University Corporation Tottori University, Tottorishi, JP;

Inventors:

Yohei Kono, Yonago, JP;

Noriko Itaba, Tottorishi, JP;

Goshi Shiota, Tottorishi, JP;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/81 (2006.01); C12N 5/0775 (2010.01); A61K 35/28 (2015.01);
U.S. Cl.
CPC ...
C07K 14/8146 (2013.01); A61K 35/28 (2013.01); C12N 5/0663 (2013.01); A61K 38/00 (2013.01);
Abstract

[Problem] To provide a composition and a cell sheet which are highly effective for inhibiting fibrosis, or cells having fibrosis-inhibiting activity, which are useful in regenerative medicine. [Solution] A medium containing IC-2 or a related compound is inoculated with mesenchymal stem cells or bone marrow mononuclear cells, and the cells are cultured for a prescribed period of time while the IC-2 or related compound is maintained at a constant concentration, thereby allowing a composition and a cell sheet which are highly effective for inhibiting fibrosis, or cultured cells having fibrosis-inhibiting activity, to be obtained.


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