The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2024

Filed:

Jun. 08, 2021
Applicant:

Industry-university Cooperation Foundation Hanyang University Erica Campus, Ansan-si, KR;

Inventors:

Dong Woo Lim, Ansan-si, KR;

Jae Sang Lee, Ansan-si, KR;

Min Jung Kang, Bucheon-si, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61L 27/22 (2006.01); A61L 27/52 (2006.01); C07K 7/06 (2006.01); C07K 14/78 (2006.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); A61L 27/22 (2013.01); A61L 27/52 (2013.01); C07K 7/06 (2013.01); C07K 14/78 (2013.01);
Abstract

Disclosed is a polypeptide having a phase transition behavior, wherein the polypeptide consists of a Val-Pro-Gly-Xaa-Gly pentapeptide repeat or a Val-Pro-Ala-Xaa-Gly) pentapeptide repeat, and the polypeptide includes a [Val-Pro-Gly-Xaa-Gly]n or a [Val-Pro-Ala-Xaa-Gly]n (SEQ ID NO:2) pentapeptide repeat. In addition, the present invention provides a multi-stimuli polypeptide composed of polypeptide-calmodulin-polypeptide having a phase transition behavior and a hydrogel prepared using the same. A dynamic protein hydrogel according to the present invention may be used as a drug carrier, as a scaffold for tissue engineering or as a kit for tissue or organ regeneration.


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