The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
Apr. 09, 2021
Applicant:
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Inventors:
Dmitriy Gremyachinskiy, San Francisco, CA (US);
Christos Tzitzilonis, Redwood City, CA (US);
Assignee:
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/315 (2006.01); C07K 1/107 (2006.01); A61K 47/64 (2017.01); C07K 19/00 (2006.01); C12N 9/12 (2006.01); C12N 9/52 (2006.01); C12N 15/62 (2006.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
C07K 14/315 (2013.01); A61K 47/64 (2017.08); A61K 47/6415 (2017.08); C07K 1/1072 (2013.01); C07K 1/1077 (2013.01); C07K 19/00 (2013.01); C12N 9/1205 (2013.01); C12N 9/1241 (2013.01); C12N 9/52 (2013.01); C12N 15/62 (2013.01); C12Q 1/68 (2013.01); C07K 2319/03 (2013.01); C07K 2319/20 (2013.01); C12Y 207/07 (2013.01);
Abstract
The present disclosure relates to relates methods and associated compositions that provide fast, efficient site-selective conjugation of a protein, such as the pore-forming protein α-hemolysin, to a biomolecule, such as a DNA polymerase, and the use of such site-selective protein-biomolecule conjugates in nanopore devices and methods.