The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
Dec. 22, 2020
Applicant:
Nsc Therapeutics Gmbh, St. Radegund, AT;
Inventors:
Assignee:
NSC Therapeutics GmbH, St. Radegund, AT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/10 (2006.01); A61P 27/02 (2006.01);
U.S. Cl.
CPC ...
C07D 513/10 (2013.01); A61P 27/02 (2018.01); C07B 2200/13 (2013.01);
Abstract
Provided are novel crystalline forms of a spiro-compound which acts as a muscarinic acetylcholine receptor agonist. In particular, isolated crystalline polymorphs of (S)-2-ethyl-8-methyl-1-thia-4,8-diazaspiro[4.5]decane-3-one are described which have favorable properties in pharmaceutical manufacture. Also provided are methods to prepare said crystalline polymorphs, and to convert them into each other as well as methods for preparing medicaments containing the same which are suitable for use in the treatment of diseases and disorders that respond to modulation of the muscarinic acetylcholine receptor.