The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
Mar. 20, 2019
Icahn School of Medicine AT Mount Sinai, New York, NY (US);
Kunal Kumar, New York, NY (US);
Peng Wang, New York, NY (US);
Roberto Sanchez, New York, NY (US);
Adolfo Garcia Ocaña, New York, NY (US);
Andrew Stewart, New York, NY (US);
Robert Devita, New York, NY (US);
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, New York, NY (US);
Abstract
Described herein are compounds having the following structure: formula (I) or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof. Also disclosed are compositions containing the compounds, methods of inhibiting activity of DYRK1 A in a cell, methods of increasing cell proliferation in a population of pancreatic beta cells, methods of treating a subject for a condition associated with insufficient insulin secretion, and methods of treating a subject for a neurological disorder.