The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
Apr. 03, 2019
Applicant:
Uab Research Foundation, Birmingham, AL (US);
Inventors:
Sadanandan E. Velu, Birmingham, AL (US);
Hui Wu, Hoover, AL (US);
Qiong Zhang, Sichuan, CN;
Bhavitavya Nijampatnam, Birmingham, AL (US);
Assignee:
UAB Research Foundation, Birmingham, AL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 333/62 (2006.01); A61P 43/00 (2006.01); A61K 6/00 (2020.01);
U.S. Cl.
CPC ...
C07D 333/62 (2013.01); A61K 6/00 (2013.01); A61P 43/00 (2018.01);
Abstract
The present invention is related to the inhibition of the formation of Streptococci biofilms through the inhibition of glucosyl transferase (Gtf). Compounds, compositions and methods for inhibitingbiofilm formation, as well as for preventing, inhibiting and/or treating the formation of dental caries, and methods of identifying compounds that prevent, inhibit and/or treat the formation of dental caries are provided.