The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
May. 14, 2019
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
Jiaming Li, Pasadena, CA (US);
Xu Chen, Pasadena, CA (US);
Tonia S. Ahmed, Pasadena, CA (US);
Brian M. Stoltz, Pasadena, CA (US);
Robert H. Grubbs, Pasadena, CA (US);
Assignee:
California Institute of Technology, Pasadena, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 405/00 (2006.01); B01J 23/46 (2006.01);
U.S. Cl.
CPC ...
C07C 405/0016 (2013.01); B01J 23/462 (2013.01); C07C 2601/10 (2017.05);
Abstract
This invention relates generally to the synthesis of Δ-Prostaglandin J product using stereoretentive ruthenium olefin metathesis catalysts supported by dithiolate ligands. Δ-Prostaglandin J products were generated with excellent selectivity (>99% Z) and in moderate to high/good yields (47% to 80% yield; 58% to 80% yield).