The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2024

Filed:

May. 22, 2020
Applicants:

Lantheus Medical Imaging, Inc., North Billerica, MA (US);

Yale University, New Haven, CT (US);

Inventors:

Albert J. Sinusas, Guilford, CT (US);

Joseph G. Akar, New Haven, CT (US);

Richard R. Cesati, Pepperell, MA (US);

Heike S. Radeke, South Grafton, MA (US);

Stephen B. Haber, Westford, MA (US);

Assignee:

Lantheus Medical Imaging, Inc., North Billerica, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); A61K 51/08 (2006.01);
U.S. Cl.
CPC ...
A61K 51/044 (2013.01); A61K 51/0459 (2013.01); A61K 51/0476 (2013.01); A61K 51/0478 (2013.01); A61K 51/0497 (2013.01); A61K 51/08 (2013.01); A61B 2576/023 (2013.01);
Abstract

The invention provides, in some embodiments, methods relating to assessing increased risk of developing atrial fibrillation (AF), and/or the likelihood of responding to particular AF therapies using imaging agents comprising an MMP inhibitor linked to an imaging moiety. The invention further provides methods for evaluating the presence of the risk of developing other cardiovascular conditions and assessing the effectiveness of treatment or other intervention for such conditions by determining MMP levels.


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