The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
Nov. 23, 2021
Applicant:
Papivax Biotech Inc., Taipei, TW;
Inventor:
Yung-Nien Chang, Elkridge, MD (US);
Assignee:
Papivax Biotech Inc., Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 35/76 (2015.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61P 31/20 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61K 35/76 (2013.01); A61K 39/39 (2013.01); A61P 35/00 (2018.01); A61K 2039/53 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/585 (2013.01);
Abstract
The present disclosure provides a DNA vaccine for a subject having a human papillomavirus (HPV)-associated disease. The DNA vaccine may include a DNA construct including a fusion gene. The fusion gene may be a subsegment of the DNA construct that includes an optimized HPV subsequence encoding at least one HPV antigen. The optimized HPV subsequence may include one or more of: an HPV-16 E6 expressing gene set forth in SEQ ID NO: 1, an HPV-16 E7 expressing gene set forth in SEQ ID NO: 2, an HPV-18 E6 expressing gene set forth in SEQ ID NO: 3, and an HPV-18 E7 expressing gene set forth in SEQ ID NO: 4.