The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2024

Filed:

Mar. 27, 2019
Applicant:

G+flas Life Sciences, Seoul, KR;

Inventors:

Sunghwa Choe, Seoul, KR;

Mi Jin Park, Seoul, KR;

Aiden Yeonghoon Park, Seoul, KR;

Jung Hak Lim, Seoul, KR;

Dong Wook Kim, Seoul, KR;

Sungyong In, Seoul, KR;

Jongjin Park, West Lafayette, IN (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 38/46 (2006.01); A61K 47/64 (2017.01); A61P 35/00 (2006.01); A61K 31/7105 (2006.01);
U.S. Cl.
CPC ...
A61K 38/465 (2013.01); A61K 31/7105 (2013.01); A61K 47/64 (2017.08); A61P 35/00 (2018.01);
Abstract

A pharmaceutical composition for treating cancer, containing a crRNA and an endonuclease as active ingredients is disclosed. The composition can be customized according to the needs of patients or cell types by specifically treating cancer cells on the basis of specific binding properties of DNA and RNA. The nuclease activity of a CRISPR PLUS system, containing both an endonuclease and an exonuclease can be activated by means of the binding between crRNA and a gene specifically found in cancer cells. Therefore, the cancer treatment effect of the composition is more specific than that of other anti-cancer agents that have been developed up till now.


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