The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2024

Filed:

Sep. 15, 2017
Applicant:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

William S. Brimijoin, Rochester, MN (US);

Liewei Wang, Rochester, MN (US);

Yang Gao, Rochester, MN (US);

Ping Chen, Rochester, MN (US);

Liyi Geng, Rochester, MN (US);

Jia Yu, Rochester, MN (US);

Judy C. Boughey, Rochester, MN (US);

Matthew P. Goetz, Rochester, MN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); A61P 35/00 (2006.01); C12N 15/86 (2006.01); C12N 9/18 (2006.01);
U.S. Cl.
CPC ...
A61K 38/465 (2013.01); A61P 35/00 (2018.01); C12N 9/18 (2013.01); C12N 15/86 (2013.01); A01K 2207/12 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0331 (2013.01); C12N 2710/10043 (2013.01); C12N 2750/14143 (2013.01); C12Y 301/01008 (2013.01);
Abstract

This document provides methods and materials for using butyrylcholinesterases (BChE) to treat cancer (e.g., triple negative breast cancer or prostate cancer). For example, methods and materials for using nucleic acid vectors (e.g., viral vectors) to express BChE polypeptides under conditions that reduce the number of cancer cells (e.g., triple negative breast cancer cells or prostate cancer cells) within a mammal (e.g., a human) and/or reduce the growth rate of cancer cells (e.g., triple negative breast cancer cells or prostate cancer cells) within a mammal (e.g., a human) are provided.


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