The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
Jan. 11, 2018
Applicant:
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Inventors:
Evanthia Galanis, Rochester, MN (US);
S. Keith Anderson, Rochester, MN (US);
Cheyne B. Kurokawa, Rochester, MN (US);
Ianko D. Iankov, Rochester, MN (US);
Assignee:
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 35/768 (2015.01); A61K 31/519 (2006.01); C12N 15/86 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
A61K 35/768 (2013.01); A61K 31/519 (2013.01); C12N 15/86 (2013.01); G01N 33/57484 (2013.01); C12N 2760/18432 (2013.01);
Abstract
This document provides methods and materials involved in treating cancer. For example, methods and materials for using an inhibitor of UFM1 activity or expression and/or an inhibitor of UFL1 activity or expression to reduce a cancer cell's ability to carry out a DDR, thereby increasing the sensitivity of cancer cells to treatment with a DNA damaging therapy such as radiation or chemotherapy, are provided.