The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
Oct. 01, 2021
Applicant:
Lunella Biotech, Inc., Ontario, CA;
Inventors:
Michael P. Lisanti, Fulton, MD (US);
Federica Sotgia, Fulton, MD (US);
Assignee:
LUNELLA BIOTECH, INC., Ontario, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7048 (2006.01); A61K 47/54 (2017.01); A61K 31/122 (2006.01); A61K 31/165 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7048 (2013.01); A61K 31/122 (2013.01); A61K 31/165 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 47/54 (2017.08); A61K 47/542 (2017.08); A61K 47/548 (2017.08);
Abstract
Antibiotics having intrinsic anti-mitochondrial properties may be chemically modified to target the antibiotics to mitochondria, and the resulting 'antimitoscins' may have enhanced anti-cancer properties, among other advantageous properties. Also described are methods for identifying antimitoscins, methods of using antimitoscins to target cancer stem cells, and pharmaceutical compositions for treating cancer containing one or more antimitoscins as the active ingredient. Specific antimitoscins compounds and groups of antimitoscins are also disclosed.