The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
Sep. 01, 2021
Combination therapy of pd-1-targeted il-2 variant immunocytokines and antibodies against human pd-l1
Applicant:
Hoffman-la Roche Inc., Little Falls, NJ (US);
Inventors:
Laura Codarri Deak, Schlieren, CH;
Douglas Hanahan, Saint-Sulpice, CH;
Christian Klein, Schlieren, CH;
Valeria Nicolini, Schlieren, CH;
Pablo Umana, Schlieren, CH;
Stephan Wullschleger, Urdorf, CH;
Assignee:
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 35/17 (2015.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); A61K 35/15 (2015.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2013 (2013.01); A61K 35/15 (2013.01); A61K 35/17 (2013.01); A61K 38/1774 (2013.01); A61K 39/3955 (2013.01); A61P 35/00 (2018.01);
Abstract
The present invention relates to the combination therapy of specific PD-1-targeted IL-2 variant immunocytokines with specific antibodies which bind human PD-L1.