The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2024
Filed:
May. 24, 2021
Apsam Imaging Corp., Osaka, JP;
Kazuaki Nakane, Osaka, JP;
Chaoyang Yan, Nanjing, CN;
Xiangxue Wang, Cleveland, OH (US);
Yao Fu, Nanjing, CN;
Haoda Lu, Nanjing, CN;
Xiangshan Fan, Nanjing, CN;
Michael D. Feldman, Philadelphia, PA (US);
Anant Madabhushi, Cleveland, OH (US);
Jun Xu, Nanjing, CN;
APSAM Imaging Corp., Osaka, JP;
Abstract
The degree of differentiation of a cell in tissue is precisely determined. An estimating device () includes: a binarizing section () configured to generate binarized images from an image obtained by capturing an image of tissue; a Betti number calculating section () configured to calculate, for each binarized image, (i) the number of hole-shaped regions (b) each surrounded by pixels of a first pixel value and each composed of pixels of a second pixel value, (ii) the number of connected regions each composed of the pixels of the first pixel value connected together, and (iii) a ratio (R) between (i) and (ii); a statistic calculating section () configured to calculate statistics of the calculated numbers (b, b) and ratio (R); and an estimating section () configured to feed input data including the calculated statistics to a trained estimating model to output the degree of differentiation of the cell in tissue.