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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11860169 B1

PDFFull Text
Date of Patent:
Jan. 02, 2024

Filed:

Sep. 08, 2020

Method of treating and prognosing scoliotic patient subgroups

Applicant:

Chu Sainte-justine, Montreal, CA;

Inventors:

Alain Moreau, Montreal, CA;

Marie-Yvonne Akoume Ndong, Montreal, CA;

Assignee:

CHU SAINTE-JUSTINE, Montreal, CA;

Attorneys:

Lavery, de Billy, L.L.P.

Julie Gauvreau

Primary Examiner:

Elizabeth C Kemmerer

Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 33/487 (2006.01); G01N 33/53 (2006.01); A61F 5/02 (2006.01); A61K 31/4045 (2006.01); A61K 33/04 (2006.01); A61K 45/06 (2006.01); A61K 31/713 (2006.01); A61K 38/19 (2006.01); C12N 15/113 (2010.01); A61K 38/08 (2019.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); A61F 5/02 (2013.01); A61F 5/026 (2013.01); A61K 31/4045 (2013.01); A61K 31/713 (2013.01); A61K 33/04 (2013.01); A61K 38/19 (2013.01); A61K 45/06 (2013.01); C12N 15/1138 (2013.01); G01N 33/48728 (2013.01); A61K 38/08 (2013.01); C12N 2310/14 (2013.01); C12N 2320/30 (2013.01); G01N 33/53 (2013.01); G01N 2333/04 (2013.01); G01N 2333/726 (2013.01); G01N 2800/10 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention provides a method of treating a subject in need thereof comprising classifying the subject into functional group FG1, FG2 or FG3, wherein i) when the subject is classified into the FG1 functional group, (A) the level of OPN or the activity of OPN in said subject is increased; (B) the subject is not treated with a brace; or (C) a combination of (A) and (B); and ii) when the subject is classified into the FG2 or FG3 functional group, (A) the level of OPN or the activity of OPN in said subject is decreased; (B) the subject is treated with a brace; or (C) a combination of (A) and (B).

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