The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2024

Filed:

Nov. 15, 2021
Applicant:

Creatv Microtech, Inc., Potomac, MD (US);

Inventors:

Olga Makarova, Naperville, IL (US);

Cha-Mei Tang, Potomac, MD (US);

Peixuan Zhu, Derwood, MD (US);

Shuhong Li, North Potomac, MD (US);

Daniel Adams, Kensington, MD (US);

Platte T. Amstutz, Vienna, VA (US);

Assignee:

CREATV MICROTECH, INC., Potomac, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 1/40 (2006.01); B01L 3/00 (2006.01); B01D 39/16 (2006.01); B01D 29/00 (2006.01); B01L 9/00 (2006.01); B01D 71/46 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5005 (2013.01); B01D 29/00 (2013.01); B01D 39/16 (2013.01); B01D 39/1692 (2013.01); B01D 71/46 (2013.01); B01L 3/50 (2013.01); B01L 3/5635 (2013.01); B01L 9/00 (2013.01); G01N 1/4005 (2013.01); G01N 1/4077 (2013.01); B01D 2239/0421 (2013.01); B01L 3/502 (2013.01); B01L 2300/0681 (2013.01); G01N 2001/4088 (2013.01); Y10T 29/49826 (2015.01); Y10T 29/49963 (2015.01);
Abstract

A microfilter having a hydrophilic surface and suited for size-based capture and analysis of cells, such as circulating cancer cells, from whole blood and other human fluids is disclosed. The filter material is photo-definable, allowing the formation of precision pores by UV lithography. Exemplary embodiments provide a device that combines a microfilter with 3D nanotopography in culture scaffolds that mimic the 3D in vivo environment to better facilitate growth of captured cells.


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