The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2024
Filed:
May. 09, 2016
Applicant:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Inventors:
Christina D. Smolke, Menlo Park, CA (US);
Stephanie Galanie, Palo Alto, CA (US);
Isis Trenchard, Redwood City, CA (US);
Catherine Thodey, Mountain View, CA (US);
Yanran Li, Mountain View, CA (US);
Assignee:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 17/12 (2006.01); C12N 15/52 (2006.01); C12P 41/00 (2006.01); C12N 9/04 (2006.01); C12N 9/02 (2006.01); C12N 15/62 (2006.01);
U.S. Cl.
CPC ...
C12P 17/12 (2013.01); C12N 9/0006 (2013.01); C12N 9/0071 (2013.01); C12N 15/52 (2013.01); C12N 15/62 (2013.01); C12P 41/002 (2013.01); C12Y 101/01247 (2013.01); C12N 2800/22 (2013.01);
Abstract
A method of epimerizing an (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid is provided. The method comprises contacting the (S)-1-benzylisoquinoline alkaloid with at least one enzyme. Contacting the (S)-1-benzylisoquinoline alkaloid with the at least one enzyme converts the (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid.