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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11859219 B1

PDFFull Text
Date of Patent:
Jan. 02, 2024

Filed:

Dec. 29, 2017

Methods of altering a target nucleotide sequence with an rna-guided nuclease and a single guide rna

Applicant:

Flagship Pioneering Innovations V, Inc., Cambridge, MA (US);

Inventors:

Yajie Niu, Lexington, MA (US);

Kristine Yu, Cambridge, MA (US);

Frank Anthony Skraly, Watertown, MA (US);

Randall William Shultz, Acton, MA (US);

John P. Casey, Jr., Boston, MA (US);

Brian Prescott Fiske, Cambridge, MA (US);

Assignee:

Flagship Pioneering Innovations V, Inc., Cambridge, MA (US);

Attorney:

Klarquist Sparkman, LLP

Primary Examiner:

Charles Logsdon

Assistant Examiner:

Wayne Zhong

Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 15/82 (2006.01); A01H 4/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); C12N 15/8202 (2013.01); A01H 4/008 (2013.01); C12N 2310/20 (2017.05);
Abstract

Disclosed herein are compositions and methods for effecting alterations at a defined location in the genome of a plant cell or plant protoplast. Further disclosed are methods using an RNA-guided nuclease to alter a target nucleotide sequence in a cell or protoplast of a plant; embodiments of such methods include treatments with chemical or physical reagents or treatment of the cell or protoplast with a specific thermal regime, such as a heat treatment.

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Niu, Yajie. (2024). Methods of altering a target nucleotide sequence with an rna-guided nuclease and a single guide rna (U.S. Patent No. 11859219). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11859219

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