The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2024

Filed:

Jul. 07, 2020
Applicants:

Ganymed Pharmaceuticals Gmbh, Mainz, DE;

Johannes Gutenberg-universitat Mainz, Mainz, DE;

Inventors:

Ugur Sahin, Mainz, DE;

Özlem Türeci, Mainz, DE;

Michael Koslowski, Frankfurt, DE;

Korden Walter, Wiesbaden, DE;

Stefan Woll, Nackenheim, DE;

Maria Kreuzberg, Mainz, DE;

Bernd Hubner, Munich, DE;

Michael Erdeljan, Hochheim am Main, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/30 (2006.01); C12N 5/10 (2006.01); C12N 15/00 (2006.01); C12N 15/09 (2006.01); C12N 15/13 (2006.01); C07K 16/02 (2006.01); A61K 39/00 (2006.01); C12N 15/63 (2006.01); C12N 5/16 (2006.01);
U.S. Cl.
CPC ...
C07K 16/02 (2013.01); C07K 16/30 (2013.01); A61K 2039/505 (2013.01); C07K 2317/14 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/52 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C12N 5/10 (2013.01); C12N 5/16 (2013.01); C12N 15/00 (2013.01); C12N 15/09 (2013.01); C12N 15/63 (2013.01); C12N 2510/00 (2013.01); C12N 2800/00 (2013.01);
Abstract

The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing Claudin-6 (CLDN6), including tumor-related diseases such as ovarian cancer, lung cancer, gastric cancer, breast cancer, hepatic cancer, pancreatic cancer, skin cancer, malignant melanoma, head and neck cancer, sarcoma, bile duct cancer, cancer of the urinary bladder, kidney cancer, colon cancer, placental choriocarcinoma, cervical cancer, testicular cancer, and uterine cancer.


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