The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2024

Filed:

Oct. 22, 2020
Applicants:

Innovative Cellular Therapeutics Holdings, Ltd., Grand Cayman, KY;

Innovative Cellular Therapeutics, Inc., Rockville, MD (US);

Inventors:

Chengfei Pu, Shanghai, CN;

Dongqi Chen, Shanghai, CN;

Xiaogang Shen, Shanghai, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/725 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); C07K 14/70578 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01);
Abstract

Embodiments relate to a modified cell engineered to comprise a modified TCR-CD3 complex, wherein the CD3γ, ζ-chain, CD3ε, and/or CD3δ chains of the modified TCR-CD3 complex are linked to one or more co-stimulatory signaling domains.


Find Patent Forward Citations

Loading…