The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2024
Filed:
Jun. 15, 2022
Nucleic acid constructs encoding chimeric nk receptor, cells containing, and therapeutic use thereof
Applicant:
The Trustees of Dartmouth College, Hanover, NH (US);
Inventors:
Tong Zhang, Beijing, CN;
Charles L Sentman, West Lebanon, NH (US);
Assignee:
THE TRUSTEES OF DARTMOUTH COLLEGE, Hanover, NH (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61K 38/10 (2006.01); C07K 14/715 (2006.01); A61K 35/17 (2015.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 14/705 (2013.01); A61K 35/17 (2013.01); A61K 38/10 (2013.01); A61K 45/06 (2013.01); C07K 14/715 (2013.01);
Abstract
The present invention relates to chimeric immune receptor molecules for reducing or eliminating tumors. The chimeric receptors are composed a C-type lectin-like natural killer cell receptor, or a protein associated therewith, fused to an immune signaling receptor containing an immunoreceptor tyrosine-based activation motif. Methods for using the chimeric receptors are further provided.
Zhang, Tong. (2024). Nucleic acid constructs encoding chimeric nk receptor, cells containing, and therapeutic use thereof (U.S. Patent No. 11858976). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11858976
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