The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2024
Filed:
Feb. 23, 2022
Applicant:
Pliant Therapeutics, Inc., South San Francisco, CA (US);
Inventors:
Katerina Leftheris, South San Francisco, CA (US);
Maureen Reilly, Burlingame, CA (US);
Darren Finkelstein, Palo Alto, CA (US);
Nicole Cooper, Oakland, CA (US);
Christopher Bailey, Mountain View, CA (US);
Jacob Cha, San Bruno, CA (US);
Assignee:
PLIANT THERAPEUTICS, INC., South San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 519/00 (2013.01);
Abstract
The invention relates to compounds of formula (A): or a salt thereof, wherein R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, n, and G are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are αβintegrin inhibitors that are useful for treating fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).