The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2024
Filed:
May. 19, 2023
Applicant:
Theravance Biopharma R&d Ip, Llc, South San Francisco, CA (US);
Inventor:
Grahame Woollam, Basel, CH;
Assignee:
THERAVANCE BIOPHARMA R&D IP, LLC, South San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/62 (2006.01); C07D 401/12 (2006.01); A61K 31/4545 (2006.01); A61K 9/12 (2006.01); A61K 9/16 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 211/62 (2013.01); A61K 9/124 (2013.01); A61K 9/1623 (2013.01); A61K 31/4545 (2013.01); A61K 45/06 (2013.01); C07D 401/12 (2013.01); C07B 2200/13 (2013.01);
Abstract
The invention provides two crystalline freebase forms of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester. The invention also provides pharmaceutical compositions comprising the crystalline freebase or prepared using the crystalline freebases; processes and intermediates for preparing the crystalline freebases; and methods of using the crystalline freebases to treat a pulmonary disorder.