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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11857663 B1

PDFFull Text
Date of Patent:
Jan. 02, 2024

Filed:

Apr. 08, 2022

Stable silk protein fragment compositions

Applicant:

Evolved BY Nature, Inc., Medford, MA (US);

Inventors:

Gregory H. Altman, Providence, RI (US);

Rebecca L. Lacouture, Needham, MA (US);

Rachel Lee Dow, Medford, MA (US);

Rachel M. Lind, Somers, NY (US);

Dylan S. Haas, Yorktown Heights, NY (US);

Assignee:

EVOLVED BY NATURE, INC., Medford, MA (US);

Attorney:

Morgan, Lewis & Bockius LLP

Primary Examiner:

Kevin S Orwig

Int. Cl.
CPC ...
A61K 9/08 (2006.01); A61K 8/02 (2006.01); A61K 38/01 (2006.01); A61K 8/64 (2006.01); C07K 1/12 (2006.01); C07K 14/435 (2006.01); A61K 38/00 (2006.01); A61K 8/98 (2006.01); A61Q 19/02 (2006.01); A61K 8/92 (2006.01); A61K 8/04 (2006.01); A61K 8/19 (2006.01); A61K 8/9789 (2017.01); A61K 8/9794 (2017.01); A61K 8/97 (2017.01); A61K 31/375 (2006.01); A61K 45/06 (2006.01); A61K 47/02 (2006.01); A61K 47/12 (2006.01); A61K 47/36 (2006.01); A61K 8/27 (2006.01); A61K 8/29 (2006.01); A61K 8/67 (2006.01); A61K 8/73 (2006.01); A61Q 17/04 (2006.01); A61Q 19/00 (2006.01); A61Q 19/08 (2006.01); A45D 33/00 (2006.01); A61K 8/365 (2006.01); A61K 8/49 (2006.01);
U.S. Cl.
CPC ...
A61K 8/64 (2013.01); A45D 33/00 (2013.01); A61K 8/02 (2013.01); A61K 8/0216 (2013.01); A61K 8/042 (2013.01); A61K 8/19 (2013.01); A61K 8/27 (2013.01); A61K 8/29 (2013.01); A61K 8/365 (2013.01); A61K 8/4953 (2013.01); A61K 8/676 (2013.01); A61K 8/735 (2013.01); A61K 8/922 (2013.01); A61K 8/97 (2013.01); A61K 8/9789 (2017.08); A61K 8/9794 (2017.08); A61K 8/987 (2013.01); A61K 9/08 (2013.01); A61K 31/375 (2013.01); A61K 38/00 (2013.01); A61K 38/012 (2013.01); A61K 45/06 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/36 (2013.01); A61Q 17/04 (2013.01); A61Q 19/00 (2013.01); A61Q 19/007 (2013.01); A61Q 19/02 (2013.01); A61Q 19/08 (2013.01); C07K 1/12 (2013.01); C07K 14/43586 (2013.01); A61K 2800/591 (2013.01); A61K 2800/72 (2013.01); A61K 2800/74 (2013.01); A61K 2800/75 (2013.01);
Abstract

A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.

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