The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2024
Filed:
Mar. 30, 2020
Jenkem Technology Co., Ltd. (Tianjin), Tianjin, CN;
Zewang Feng, Tianjin, CN;
Qingbin Wang, Tianjin, CN;
Jinliang Wang, Tianjin, CN;
Yanping Song, Tianjin, CN;
Yanli Xiong, Tianjin, CN;
Leimin Wang, Tianjin, CN;
Jinghui Du, Tianjin, CN;
Xuan Zhao, Tianjin, CN;
JenKem Technology Co., Ltd. (Tianjin), Tianjin, CN;
Abstract
The disclosure discloses a linker compound, a polyethylene glycol-linker conjugate and a derivative thereof, and a polyethylene glycol-linker-drug conjugate. The linker compound as well as the conjugate thereof with the polyethylene glycol and the derivative thereof may be used for modifying a drug, and a modification reaction is simple and easy to carry out. Moreover, a reaction yield is high, and an application range of the modified drug is wide. The modified drugs gradually degrade from a chain of the conjugate in vivo, and may stay in a lesion (such as a cancer site) for a longer period of time, achieving purposes of sustained and controlled release, reducing an administration frequency, and greatly improving a bioavailability of the drug and a patient compliance.