The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2024

Filed:

Apr. 20, 2019
Applicant:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Song Li, Wexford, PA (US);

Jingjing Sun, Pittsburgh, PA (US);

Yichao Chen, Pittsburgh, PA (US);

Yixian Huang, Pittsburgh, PA (US);

Yanhua Liu, Pittsburgh, PA (US);

Binfeng Lu, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/58 (2017.01); A61K 47/54 (2017.01); A61K 9/107 (2006.01); A61K 31/65 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 47/58 (2017.08); A61K 9/1075 (2013.01); A61K 31/65 (2013.01); A61K 47/549 (2017.08); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2310/351 (2013.01);
Abstract

A formulation includes a plurality of polymers including a hydrophobic polymer backbone (for example, formed via radical polymerization), a first plurality of pendant groups attached to the hydrophobic polymer backbone and including at least one cationic group, and a second plurality of pendant groups attached to the hydrophobic polymer backbone and including at least one hydrophilic polymer, a first therapeutic compound, and a second therapeutic compound, wherein the second therapeutic compound is different from the first therapeutic compound and includes a nucleic acid.


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