The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2024
Filed:
Apr. 02, 2018
Applicant:
Acceleron Pharma Inc., Cambridge, MA (US);
Inventors:
Ravindra Kumar, Acton, MA (US);
Rajasekhar Naga Venkata Sai Suragani, Wrentham, MA (US);
Jia Li, Danvers, MA (US);
Assignee:
Acceleron Pharma Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61K 38/17 (2006.01); A61P 21/00 (2006.01); A61K 31/7125 (2006.01); A61K 45/06 (2006.01); C07K 14/71 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 38/1841 (2013.01); A61K 31/7125 (2013.01); A61K 38/18 (2013.01); A61K 45/06 (2013.01); A61P 21/00 (2018.01); C07K 14/71 (2013.01); C12N 15/113 (2013.01); A61K 38/179 (2013.01); C07K 2319/30 (2013.01); C07K 2319/32 (2013.01); C12N 2310/11 (2013.01); C12N 2320/31 (2013.01);
Abstract
In certain aspects, the disclosure provides compositions and methods for treating spinal muscular atrophy. For example, in some embodiments, the disclosure provides ALK4:ActRIIB antagonists that may be used to treat spinal muscular atrophy, particularly treating one or more complications of spinal muscular atrophy including, for example, increasing muscle mass muscle strength, and bone mineral density.