The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2024

Filed:

Feb. 03, 2021
Applicant:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Inventors:

Sona Ghadimi, Charlottesville, VA (US);

Changyu Sun, Charlottesville, VA (US);

Xue Feng, Zion Crossroads, VA (US);

Craig H. Meyer, Charlottesville, VA (US);

Frederick H. Epstein, Charlottesville, VA (US);

Assignee:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06T 7/00 (2017.01); A61B 5/00 (2006.01); A61B 5/02 (2006.01); G06T 7/11 (2017.01); G16H 30/40 (2018.01); G06N 3/08 (2023.01); G01R 33/56 (2006.01); A61B 5/055 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0044 (2013.01); A61B 5/02028 (2013.01); A61B 5/7267 (2013.01); A61B 5/7278 (2013.01); G01R 33/56 (2013.01); G06N 3/08 (2013.01); G06T 7/0012 (2013.01); G06T 7/11 (2017.01); G16H 30/40 (2018.01); A61B 5/055 (2013.01); A61B 2576/023 (2013.01); G06T 2207/10088 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30048 (2013.01);
Abstract

A method of cardiac strain analysis uses displacement encoded magnetic resonance image (MRI) data of a heart of the subject and includes generating a phase image for each frame of the displacement encoded MRI data. Phase images include potentially phase-wrapped measured phase values corresponding to pixels of the frame. A convolutional neural network CNN computes a wrapping label map for the phase image, and the wrapping label map includes a respective number of phase wrap cycles present at each pixel in the phase image. Computing an unwrapped phase image includes adding a respective phase correction to each of the potentially-wrapped measured phase values of the phase image, and the phase correction is based on the number of phase wrap cycles present at each pixel. Computing myocardial strain follows by using the unwrapped phase image for strain analysis of the subject.


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