The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2024

Filed:

Mar. 08, 2021
Applicants:

Inter Science Gmbh, Gisikon, CH;

Rm2 Technology Llc, Rancho Mission Viejo, CA (US);

Inventors:

Boris Rubinsky, El Cerrito, CA (US);

Paul Mikus, Rancho Mission Viejo, CA (US);

Liel Rubinsky, El Cerrito, CA (US);

Michael Klaus Stehling, Rödermark, DE;

Enric Günther, Hattersheim, DE;

Assignees:

Inter Science GmbH, Gisikon, CH;

RM2 Technology LLC, Miami, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 18/12 (2006.01); A61N 1/32 (2006.01); A61B 18/14 (2006.01); A61N 1/20 (2006.01); A61B 18/00 (2006.01); A61B 5/145 (2006.01);
U.S. Cl.
CPC ...
A61B 18/1206 (2013.01); A61B 18/1402 (2013.01); A61N 1/205 (2013.01); A61N 1/327 (2013.01); A61B 5/14539 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00613 (2013.01); A61B 2018/00827 (2013.01); A61B 2018/00994 (2013.01); A61B 2018/1266 (2013.01); A61B 2018/1472 (2013.01);
Abstract

Example methods and apparatuses are disclosed for providing tissue ablation through electrolysis, electroporation, or a combination thereof. A way to deliver the combination through a pulse that has an element of gradual decay and can thereby reduce both muscle contraction and electric breakdown discharge at the electrodes is disclosed. The apparatus disclosed may include an electrode, a power supply, and a controller. The controller may control a charge applied to the electrode to induce a direct current through a treatment site to produce electrolysis products and a voltage to produce electroporation. The duration and magnitude of the charge applied may determine the dose of the products and the degree of the permeabilization of cells in the treatment site.


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