The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2024

Filed:

Jan. 25, 2018
Applicant:

The University of Tokyo, Tokyo, JP;

Inventors:

Hiromitsu Nakauchi, Tokyo, JP;

Tomoyuki Yamaguchi, Tokyo, JP;

Sanae Hamanaka, Tokyo, JP;

Hideyuki Sato, Tokyo, JP;

Hideki Masaki, Tokyo, JP;

Naoaki Mizuno, Tokyo, JP;

Motoo Watanabe, Tokyo, JP;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); A61P 37/06 (2006.01); A61K 31/573 (2006.01); C12N 15/09 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0271 (2013.01); A61K 31/573 (2013.01); A61P 37/06 (2018.01); A01K 2217/05 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/035 (2013.01); C12N 15/09 (2013.01);
Abstract

The present invention has found that chimeric animals suffer from noticeable inflammation after birth, though neither immune response nor inflammation in the fetal period of these animals has been reported hitherto. This is an unexpected finding since chimeric animals in the fetal period were exclusively analyzed in prior studies and thus it is deemed that immunotolerance has been theoretically established therein. The present invention provides a composition for suppressing immune response or inflammation in the fetal period of a born chimeric animal.


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