The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2023
Filed:
Oct. 27, 2020
Yeda Research and Development Co. Ltd., Rehovot, IL;
Universitätsklinikum Hamburg-eppendorf, Hamburg, DE;
Eran Ovadia, Mevasseret Zion, IL;
Irun R. Cohen, Rehovot, IL;
Johannes Herkel, Hamburg, DE;
Raanan Margalit, Rehovot, IL;
Meirav Pevsner-Fischer, Nes Ziona, IL;
Yeda Research and Development Co. Ltd., Rehovot, IL;
Universitätsklinikum Hamburg-Eppendorf, Hamburg, DE;
Abstract
The present invention relates to uses of a peptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 2, analogues and derivatives thereof, for the treatment of neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS). The present invention further provides a method for assessing responsiveness to treatment with the peptide of the invention. In addition, the present invention relates to prognosis of ALS progression, using Akt and phosphorylated Akt as biomarkers.