The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2023
Filed:
Jun. 09, 2021
Applicant:
University of Massachusetts, Boston, MA (US);
Inventors:
Guangping Gao, Westborough, MA (US);
Yi Lu, Shanghai, CN;
Qiang Zheng, Chengdu, CN;
Xun Xu, Shanghai, CN;
Phillip D. Zamore, Northborough, MA (US);
Phillip Tai, Worcester, MA (US);
Assignee:
University of Massachusetts, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01); C12N 15/86 (2006.01); C12N 15/11 (2006.01); A61P 27/02 (2006.01); A61K 9/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/0019 (2013.01); A61K 9/0048 (2013.01); A61P 27/02 (2018.01); C12N 15/111 (2013.01); C12N 15/86 (2013.01); A61K 48/00 (2013.01); C12N 2310/113 (2013.01); C12N 2310/141 (2013.01); C12N 2320/32 (2013.01); C12N 2330/51 (2013.01); C12N 2750/14122 (2013.01); C12N 2750/14143 (2013.01);
Abstract
The disclosure relates, in some aspects, to compositions and methods for treating corneal disease (e.g., corneal neovascularization. In some embodiments, the disclosure relates to rAAV-mediated delivery of an cornea-associated transgene to a subject. In some embodiments, the rAAV transduces the corneal tissue of a subject.