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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11851653 B1

PDFFull Text
Date of Patent:
Dec. 26, 2023

Filed:

Dec. 01, 2016

Materials and methods for treatment of alpha-1 antitrypsin deficiency

Applicant:

Crispr Therapeutics Ag;

Inventors:

Chad Albert Cowan, Cambridge, MA (US);

Roman Lvovitch Bogorad, Cambridge, MA (US);

Jeffrey Li, Cambridge, MA (US);

Ante Sven Lundberg, Cambridge, MA (US);

Matthias Johannes John, Cambridge, MA (US);

Jeffrey William Stebbins, Cambridge, MA (US);

Thao Thi Nguyen, Cambridge, MA (US);

Assignee:

CRISPR THERAPEUTICS AG, Zug, CH;

Attorney:

Sheppard, Mullin, Richter & Hampton LLP

Primary Examiner:

Anoop K Singh

Assistant Examiner:

David A Montanari

Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/10 (2006.01); A61K 9/00 (2006.01); A61K 31/7088 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/111 (2013.01); A61K 9/0019 (2013.01); A61K 31/7088 (2013.01); C12N 9/22 (2013.01); C12N 15/102 (2013.01); A61K 48/00 (2013.01); C12N 2310/20 (2017.05); C12N 2320/30 (2013.01); C12N 2320/32 (2013.01); C12N 2800/80 (2013.01);
Abstract

The present application provides materials and methods for treating a patient with Alpha-1 antitrypsin deficiency (AATD) both ex vivo and in vivo. In addition, the present application provides materials and methods for editing the SERPINA1 gene in a cell by genome editing.

Find Patent Forward Citations

Cowan, Chad. (2023). Materials and methods for treatment of alpha-1 antitrypsin deficiency (U.S. Patent No. 11851653). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11851653

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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