The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 26, 2023

Filed:

Jul. 30, 2020
Applicant:

Ablynx N.v., Ghent-Zwijnaarde, BE;

Inventors:

Peter Schotte, De Pinte, BE;

Manu De Groeve, Nieuwerkerken, BE;

Assignee:

Ablynx N.V., Zwijnaarde, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C07K 16/18 (2006.01); C07K 14/39 (2006.01); C12N 15/09 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); C07K 14/39 (2013.01); C12N 15/09 (2013.01); C12P 21/02 (2013.01); C07K 2317/14 (2013.01); C07K 2317/35 (2013.01); C07K 2317/569 (2013.01); C07K 2317/94 (2013.01);
Abstract

Methods are provided for the manufacture of polypeptides comprising at least one immunoglobulin variable domain that result in an increased yield. The methods are based on simultaneous enhancement of one or more auxiliary proteins in the host.


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