The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2023
Filed:
Oct. 31, 2012
Applicant:
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Inventors:
Taichi Kuramochi, Shizuoka, JP;
Meiri Kawazoe, Shizuoka, JP;
Naoka Hironiwa, Shizuoka, JP;
Tomoyuki Igawa, Shizuoka, JP;
Assignee:
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); C07K 16/2866 (2013.01); C07K 16/303 (2013.01); C07K 16/468 (2013.01); C07K 2317/31 (2013.01); C07K 2317/522 (2013.01);
Abstract
It was found that association between CH1 and CL can be suppressed by substituting amino acids that exist on the interface between CH1 and CL with electrically-charged amino acids, and that formation of heterogeneous molecules is enabled more efficiently than by introducing knobs into holes mutations into CH3 domain.
Kuramochi, Taichi. (2023). Antigen-binding molecule having regulated conjugation between heavy-chain and light-chain (U.S. Patent No. 11851476). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11851476
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile