The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 26, 2023

Filed:

Jun. 12, 2020
Applicant:

Quantumdx Group Limited, Newcastle Upon Tyne, GB;

Inventors:

Jonathan O'Halloran, Newcastle Upon Tyne, GB;

Heather Murton, Newcastle Upon Tyne, GB;

Stephen Osborne, Newcastle Upon Tyne, GB;

Eduardo Boada, Newcastle Upon Tyne, GB;

Jonathan Salmon, Newcastle Upon Tyne, GB;

Assignee:

QUANTUMDX GROUP LIMITED, Newcastle Upon Tyne, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); G01N 33/56966 (2013.01); B01L 2200/0631 (2013.01); B01L 2200/0668 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2400/0424 (2013.01);
Abstract

Methods and devices for concentrating target cells using dielectrophoresis (DEP) are disclosed. The method allows relatively high throughput of sample through a microfluidic device in order to allow rapid capture of target cells even when they are present in low concentrations within the sample. The method utilizes multiple chambers through which samples will flow, the chambers arranged such that the first capture area has a larger area and faster flow rate than a second chamber, the second chamber being positioned downstream of the first capture area and being smaller with a slower flow rate to further concentrate the material captured in the first capture area.


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