The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 26, 2023

Filed:

Oct. 26, 2020
Applicant:

Northeastern University, Boston, MA (US);

Inventors:

Devyesh Rana, Burlington, MA (US);

Sidi A. Bencherif, Boston, MA (US);

Nasim Annabi, Los Angeles, CA (US);

Assignee:

Northeastern University, Boston, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 27/26 (2006.01); A61L 27/52 (2006.01); A61K 47/32 (2006.01); A61K 47/58 (2017.01); A61K 47/36 (2006.01); A61K 35/15 (2015.01);
U.S. Cl.
CPC ...
A61L 27/26 (2013.01); A61K 35/15 (2013.01); A61K 47/32 (2013.01); A61K 47/36 (2013.01); A61K 47/58 (2017.08); A61L 27/52 (2013.01); A61L 2300/204 (2013.01); A61L 2400/06 (2013.01);
Abstract

Disclosed herein are functionalized dopamine derivatives comprising an optionally substituted acrylic acid moiety and optionally a polyethylene glycol linking moiety. The functionalized dopamine derivatives are useful in cryogel formulations to improve the adhesivity of the cryogel, while preventing undesirable oxidation typically associated with dopamine-containing hydrogels and cryogels. Properties such as cryogel adhesivity, pore size, and interconnectivity are tunable features. Also provided herein are methods of treating a wound or promoting tissue regeneration with a cryogel of the invention or a formulation comprising such a cryogel.


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