The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 19, 2023
Filed:
Jun. 28, 2018
Applicant:
Universitätsklinikum Hamburg-eppendorf, Hamburg, DE;
Inventor:
Thomas Renné, Hamburg, DE;
Assignee:
Universitaetsklinikum Hamburg-Eppendorf, Hamburg, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/36 (2006.01); G01N 33/86 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/86 (2013.01); C07K 16/36 (2013.01); G01N 33/6854 (2013.01); C07K 2317/75 (2013.01);
Abstract
The present invention relates to a binding molecule, in particular an antibody or binding fragment thereof, capable of activating FXII, which binds to the proline rich domain of FXII. In particular, the invention is directed to FXII activating antibodies or binding fragments thereof which binds to the proline rich domain of FXII. The invention also encompasses the use of the binding molecule directed to the proline rich domain of FXII as blood coagulation activator, e.g. in diagnostic blood coagulation tests. Corresponding methods and blood coagulation test are also encompassed.