The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2023

Filed:

Apr. 03, 2019
Applicant:

Cellular Research, Inc., San Jose, CA (US);

Inventors:

Eleen Shum, San Jose, CA (US);

Glenn Fu, San Jose, CA (US);

Craig Betts, San Jose, CA (US);

Assignee:

Becton, Dickinson and Company, Franklin Lakes, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12Q 1/6874 (2018.01); C12Q 1/6806 (2018.01); G16B 25/00 (2019.01); G16B 25/10 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C12N 15/1065 (2013.01); C12N 15/1093 (2013.01); C12Q 1/6806 (2013.01); G16B 25/00 (2019.02); G16B 25/10 (2019.02);
Abstract

This disclosure provides methods and compositions for removing one or more high abundance species from a plurality of nucleic acid molecules. In some embodiments, the methods and compositions can be used for normalizing nucleic acid libraries. In some embodiments, molecular labels are used in conjunction with the methods and compositions disclosed herein to improve sequencing efficiency.


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