The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2023

Filed:

Feb. 23, 2022
Applicant:

Lg Chem, Ltd., Seoul, KR;

Inventors:

Hye Ok Kang, Daejeon, KR;

Donggyun Kang, Daejeon, KR;

Chul Woong Kim, Daejeon, KR;

In Young Huh, Daejeon, KR;

Jung Yun Choi, Daejeon, KR;

Assignee:

LG Chem, Ltd., Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08G 63/06 (2006.01); C12P 7/625 (2022.01); C12N 1/20 (2006.01); C12N 15/70 (2006.01); C12N 9/04 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C08G 63/08 (2006.01); C12N 9/88 (2006.01);
U.S. Cl.
CPC ...
C12P 7/625 (2013.01); C08G 63/06 (2013.01); C08G 63/08 (2013.01); C12N 1/20 (2013.01); C12N 9/0006 (2013.01); C12N 9/0008 (2013.01); C12N 9/1029 (2013.01); C12N 9/13 (2013.01); C12N 9/88 (2013.01); C12N 15/70 (2013.01); C12Y 101/01027 (2013.01); C12Y 101/01028 (2013.01); C12Y 102/01003 (2013.01); C12Y 203/01 (2013.01); C12Y 208/03001 (2013.01); C12Y 402/0103 (2013.01); C12Y 402/01036 (2013.01); C12N 2510/02 (2013.01);
Abstract

The present invention relates to a novel 3-hydroxypropionate-lactate block copolymer [P(3HP-b-LA)], and a method for preparing same, and more specifically, provides a method for preparing a 3-hydroxypropionate-lactate block copolymer, and a 3-hydroxypropionate-lactate block copolymer produced thereby, the method comprising: a first culture step in which, by using recombinantimproved so as to be incapable of biosynthesizing lactic acid, P(3HP) is biosynthesized at the early stage of culturing by having glycerol as a carbon source and through 3-hydroxypropionate-generating genes and an enhanced PHA synthase; and a second culture step in which P(3HP) production is inhibited by using a carbon catabolic repression system for selectively introducing only glucose intowhen glycerol and glucose are supplied together as carbon sources, and in which polylactate is biosynthesized to an interrupted P(3HP) terminus by the enabling of the expression of a lactate synthase and a lactyl-CoA converting enzyme through an IPTG induction system.


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