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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11845803 B1

PDFFull Text
Date of Patent:
Dec. 19, 2023

Filed:

Feb. 16, 2018

Combination therapies for treatment of bcma-related cancers and autoimmune disorders

Applicant:

Fred Hutchinson Cancer Center, Seattle, WA (US);

Inventors:

Stanley R. Riddell, Sammamish, WA (US);

Damian Green, Seattle, WA (US);

Tyler Hill, Seattle, WA (US);

Assignee:

Fred Hutchinson Cancer Center, Seattle, WA (US);

Attorney:

Seed IP Law Group LLP

Primary Examiner:

Peter J Reddig

Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 31/192 (2006.01); A61K 31/216 (2006.01); A61K 31/417 (2006.01); A61K 31/4245 (2006.01); A61K 31/5513 (2006.01); C07K 14/475 (2006.01); C07K 14/52 (2006.01); C07K 16/40 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61K 9/0053 (2013.01); A61K 31/192 (2013.01); A61K 31/216 (2013.01); A61K 31/417 (2013.01); A61K 31/4245 (2013.01); A61K 31/5513 (2013.01); A61P 35/00 (2018.01); C07K 14/475 (2013.01); C07K 14/52 (2013.01); C07K 16/2887 (2013.01); C07K 16/40 (2013.01); A61K 45/06 (2013.01);
Abstract

The present disclosure relates to methods for using BCMA-specific binding molecules (such as a BCMA-specific chimeric antigen receptor or antibody) in combination with γ-secretase inhibitors, which can be done concurrently or sequentially, to treat or prevent a B-cell related proliferative disease, such as a cancer or autoimmune disease, or the like. A BCMA-specific binding molecule in combination with γ-secretase inhibitor can be used in, for example, adoptive immunotherapy.

Find Patent Forward Citations

Riddell, Stanley. (2023). Combination therapies for treatment of bcma-related cancers and autoimmune disorders (U.S. Patent No. 11845803). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11845803

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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