The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 19, 2023
Filed:
Mar. 07, 2022
Applicant:
Medimmune, Llc, Gaithersburg, MD (US);
Inventors:
Claire Dobson, Cambridge, GB;
Fiona Cusdin, Cambridge, GB;
Darren Schofield, Cambridge, GB;
Peter Cariuk, Cambridge, GB;
Elaine Hurt, Gaithersburg, MD (US);
Margareta Ek, Södertälje, SE;
Carina Johansson, Södertälje, SE;
Jenny Sandmark, Södertälje, SE;
Assignee:
MEDIMMUNE, LLC, Gaithersburg, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/22 (2006.01); A61P 35/00 (2006.01); A61P 21/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61P 21/00 (2018.01); A61P 35/00 (2018.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); C07K 2317/74 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present disclosure is directed to human GDF-15-binding antibodies and antigen-binding fragments thereof. The antibodies and fragments can be used, for example, to detect human GDF-15 and/or in methods of treating cancer or body weight loss, including cachexia, associated with over-expression of human GDF-15.