The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 19, 2023
Filed:
Dec. 15, 2021
Amgen Inc., Thousand Oaks, CA (US);
Shon Booker, Sherman Oaks, CA (US);
Matthew Paul Bourbeau, Woodland Hills, CA (US);
John R. Butler, Thousand Oaks, CA (US);
Sanne Ormholt Schroder Glad, Ballerup, DK;
Brian Alan Lanman, Woodland Hills, CA (US);
Patricia Lopez, Woodland Hills, CA (US);
Francesco Manoni, Newbury Park, CA (US);
Liping H. Pettus, Thousand Oaks, CA (US);
Ian Sarvary, Greve, DK;
Nuria A. Tamayo, Newbury Park, CA (US);
Mikkel Vestergaard, Greve, DK;
Nicholas Anthony Weires, Thousand Oaks, CA (US);
AMGEN INC., Thousand Oaks, CA (US);
Abstract
Described herein are novel PRMT5 inhibitors of Formula I and pharmaceutically acceptable salts thereof, as well as the pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity and may have use in treating proliferative, metabolic and blood disorders. Compounds of Formula I have the following structure: