The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2023

Filed:

Nov. 13, 2018
Applicants:

Rutgers, the State University of New Jersey, New Brunswick, NJ (US);

Taxis Pharmaceuticals, Inc., Monmouth Junction, NJ (US);

Inventors:

Edmond J. LaVoie, New Brunswick, NJ (US);

Hye Yeon Sagong, Monmouth Junction, NJ (US);

Ajit K. Parhi, New Brunswick, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 409/12 (2006.01); C07D 209/14 (2006.01); C07D 209/70 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 409/12 (2013.01); C07D 209/14 (2013.01); C07D 209/70 (2013.01); A61K 45/06 (2013.01);
Abstract

Disclosed herein are compounds of formula (I), or a salt thereof and compositions comprising compounds of formula I that exhibit antibacterial activities, when tested alone and/or in combination with a bacterial efflux pump inhibitor. Also disclosed are methods of treating or preventing a bacterial infection in an animal comprising administering to the animal a compound of formula I alone or in combination with the administration of a bacterial efflux pump inhibitor.


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