The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2023

Filed:

May. 26, 2021
Applicants:

Sichuan University, Chengdu, CN;

Shanxi Jinbo Bio-pharmaceutical Co., Ltd, Taiyuan, CN;

Inventors:

Yunbing Wang, Chengdu, CN;

Li Yang, Chengdu, CN;

Rifang Luo, Chengdu, CN;

Lu Lu, Chengdu, CN;

Xia Yang, Chengdu, CN;

Xingdong Zhang, Chengdu, CN;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 31/10 (2006.01); B05D 3/10 (2006.01);
U.S. Cl.
CPC ...
A61L 31/10 (2013.01); B05D 3/104 (2013.01); B05D 3/107 (2013.01); A61L 2300/252 (2013.01); A61L 2420/02 (2013.01);
Abstract

A recombinant human collagen-based multifunctional stent coating and a preparation method thereof are provided. The preparation method includes (1) activating a substrate material; (2) placing the activated substrate material in an amino compound-containing solution for a reaction to obtain an aminated substrate material; (3) placing the aminated substrate material in a polyanion electrolyte solution for a reaction, and cleaning with deionized water. The recombinant human collagen-based multifunctional stent coating prepared by the present invention effectively improves the anticoagulation and rapid endothelialization performance of biomaterials, such as vascular stent materials, and reduces the late thrombosis and restenosis problems existing in current stent materials.


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